Here's a little info on your bottle.
Sometimes old court documents can also give you some information, if you're lucky enough to find them online.
I found a court case concerning a relative's "remedy" business down in Texas, and his business was in Blair, Nebraska, which shows how far he sold his patent medicines. I just bough a 1912 real picture postcard showing one of his salesmen with his horse and buggy. The salesman is probably my 4th great-uncle Sam.