Your bottle held a wildly popular patent medicine made in Rochester, NY and Supposedly cured Kidney and Liver disease. These bottles are so popular that they're's some collecters that only collect them!! "Warners Safe..." was made by Dr. Warner, who orignally made safes Hence the word "safe" in the name and a safe embossed on the bottle. Yours was made between 1880 and 1906 When "Cure" was changed to "remedy". Hope I was any help.[]
Hello Bart. Most Kidney & Liver cures from Rochester sell for $20-30 (U.S. dollars). I say most, because there are embossing and color variations that can change the price drastically. Location (Rochester NY, London England, Melbourne Australia, Toronto Canada, Pressburg or Frankfurt Germany) is also important in the value, and a label will also raise the price.