Thanks for the try RC. Matt emailed me a copy of an 1851 ad for the product by HR Myers that mentioned 2 authorizing agents for central and southern Illinois in Peoria (Rugg & Fisher) and Springfield (Birchall & Owen). Am wondering if it could possibly be from East St Louis? Don't know if there were many manufactories "over the river" back then or not, or if there was even a east St Louis back then?truedigr said:Well, I exhausted my search in all the St. Louis city directories that were available 1840 - 1865. I couldn't find Myers or Harter dealing in medicine. There were 3 Sarsaparilla's, but not this one. They are definitely a wealth of information. The answer may be sitting in the collection mentioned above. If anyone would have that bottle, she would. RC